Sprint training increases the activities of which enzymes?

• A. Key glycolytic enzymes
• B. Mitochondrial enzymes
• C. Lipolytic enzymes
• D. Antioxidant enzymes

Answer: (A)

Sprint training pushes muscles to rely on rapid, anaerobic energy production, so the body adapts by boosting the glycolytic pathway. This means increased activity of key glycolytic enzymes—like phosphofructokinase, glyceraldehyde-3-phosphate dehydrogenase, and pyruvate kinase—to speed up glucose breakdown and generate ATP quickly during intense efforts. Enzymes such as lactate dehydrogenase also rise to help recycle NAD+ and sustain glycolysis when oxygen is limited, producing lactate as a byproduct.

In contrast, mitochondrial enzymes are more closely tied to endurance training and oxidative metabolism, while lipolytic enzymes focus on fat breakdown—less central during short, high-intensity sprints. Antioxidant enzymes may adapt, but they don’t drive the primary sprint adaptation. So the best answer reflects the upregulation of glycolytic enzymes to meet the demands of sprinting.